“America has attacked the heart of the Islamic world and must await irreparable consequences.”

In a sign of possible nervousness about a wider war, oil prices jumped by more than four percent at one point in early trading in Asia.

President Donald Trump urged Iran to end the conflict after he launched surprise strikes on a key underground uranium enrichment site at Fordo, along with nuclear facilities in Isfahan and Natanz.

“We had a spectacular military success yesterday, taking the ‘bomb’ right out of their hands (and they would use it if they could!)” he said on social media.

And while the US president did not directly advocate regime change in the Islamic Republic, he openly played with the idea — even after his aides stressed that it was not a goal of American intervention.

“It’s not politically correct to use the term ‘Regime Change,’ Trump posted on his Truth Social platform. “But if the current Iranian Regime is unable to MAKE IRAN GREAT AGAIN, why wouldn’t there be a Regime change??? MIGA!!!”

Defense Secretary Pete Hegseth told a Pentagon press briefing earlier that Iran’s nuclear program had been “devastated,” adding the operation “did not target Iranian troops or the Iranian people.”

Standing beside Hegseth, top US general Dan Caine said that while it would be “way too early” for him to determine the level of destruction, “initial battle damage assessments indicate that all three sites sustained extremely severe damage and destruction.”

Israel’s Prime Minister Benjamin Netanyahu, meanwhile, said his country’s military strikes will “finish” once the stated objectives of destroying Iran’s nuclear and missile capabilities have been achieved.

“We are very, very close to completing them,” he told reporters.

Tehran Protests

As Iran’s leaders struck defiant tones, President Masoud Pezeshkian also vowed that the United States would “receive a response” to the attacks.

People gathered Sunday in central Tehran to protest against US and Israeli attacks, waving flags and chanting slogans.

In the province of Semnan, east of the capital, 46-year-old housewife Samireh told AFP she was “truly shocked” by the strikes.

“Semnan province is very far from the nuclear facilities targeted, but I’m very concerned for the people who live near,” she said.

In an address to the nation hours after the attack, Trump claimed success for the operation, and Vice President JD Vance followed up Sunday morning.

“We know that we set the Iranian nuclear program back substantially last night,” Vance told ABC.

But he also suggested Iran still had its highly enriched uranium.

“We’re going to work in the coming weeks to ensure that we do something with that fuel,” he said. “They no longer have the capacity to turn that stockpile of highly enriched uranium to weapons-grade uranium.”

Another Khamenei advisor, Ali Shamkhani, said in a post on X that “even if nuclear sites are destroyed, the game isn’t over, enriched materials, indigenous knowledge, and political will remain.”

Rafael Grossi, director of the International Atomic Energy Agency (IAEA), told an emergency meeting of the UN Security Council that craters were visible at the Fordo facility. Still, no one had been able to assess the underground damage.

Retaliation Risk

The main US strike group was seven B-2 Spirit bombers that flew 18 hours from the American mainland to Iran.

In response to the attack, which used over a dozen massive “bunker buster” bombs, Iran’s armed forces targeted sites in Israel, including Ben Gurion airport near Tel Aviv, with at least 23 people wounded.

Nine members of the Revolutionary Guards were killed Sunday in Israeli attacks on central Iran, local media reported, while three people were killed after an ambulance was also struck.

Israeli strikes on Iran have killed more than 400 people so far, Iran’s health ministry said. Iran’s attacks on Israel have killed 24 people, according to official figures.

The United Arab Emirates, Qatar, and Oman, which had been mediating Iran-US nuclear talks, criticized the US strikes and called for de-escalation, while France, Germany, and Britain called on Tehran “not to take any further action that could destabilize the region.”

Late Sunday, the US State Department issued a “worldwide caution” for Americans, saying the conflict in the Middle East could put those traveling or living abroad at an increased security risk.

“There is the potential for demonstrations against US citizens and interests abroad,” the security alert said. “The Department of State advises US citizens worldwide to exercise increased caution.”