Pmp tablets are disposable vaping devices containing 7-Hydroxymitragynine, a potent alkaloid derived from the kratom plant (Mitragyna speciosa). These products are marketed as convenient tools for experiencing the effects of kratom without the need for traditional powders or capsules

🌿 What Is 7-Hydroxymitragynine?

7-Hydroxymitragynine (7-OH) is a naturally occurring metabolite of mitragynine, the primary active compound in kratom. It exhibits a significantly higher binding affinity to mu-opioid receptors compared to mitragynine, making it more potent in its effects. While mitragynine is associated with lower abuse potential, 7-OH demonstrates opioid-like effects and can substitute for morphine in a dose-dependent manner, raising concerns about its potential for physical dependence and addiction

🚬 How Do 7-OH Vapes Work?

7-OH vapes function similarly to standard vape pens. They heat a liquid containing 7-Hydroxymitragynine, producing vapor that's inhaled into the lungs. This method allows for rapid absorption into the bloodstream, leading to quicker onset of effects compared to traditional kratom consumption methods

⚠️ Health Risks and Regulatory Concerns

Despite their growing popularity, 7-OH vapes are not without risks. Synthetic 7-OH is up to 30 times more potent than morphine at opioid receptors, increasing the risk of dependence and overdose. These synthetic products are often deceptively marketed as "natural kratom extracts," misleading consumers into believing they are purchasing a safer, plant-based product. Due to the lack of clinical safety data, synthetic 7-OH products pose severe risks, including respiratory depression, toxicity, and addiction. Moreover, synthetic 7-OH does not meet FDA definitions of a food or dietary ingredient and is considered an unapproved drug. Many states, including Arizona, Oklahoma, Texas, and Utah, have enacted bans on synthetic 7-OH exceeding 2% of total alkaloid content in products

Kratom experts have raised an alarm about the increasing prevalence of 7-OH products in the market. These semi-synthetic products pose a public health risk and complicate the regulatory picture for kratom, to which they have been linked

🧠 User Experiences and Warnings

Some users report that 7-OH is much more mentally addicting than kratom on its own, though still more manageable than full agonist opioids. Others caution that 7-OH might not be effective when inhaled, suggesting that such vapes could either be dangerous due to other chemicals or ineffective

✅ Final Thoughts

While 7-OH vapes offer a novel method of consuming kratom's potent alkaloid, users should approach them with caution. The high potency of 7-Hydroxymitragynine, combined with the lack of regulation and potential for misleading marketing, poses significant health risks. Consumers are advised to thoroughly research products, consult healthcare professionals, and consider the legal status of such substances in their jurisdiction before use.