Several popular variations of the classic snake game include:

1. Multiplayer Snake: Players can compete against each other in real-time or take turns in a multiplayer version of the game.

2. 3D Snake: This version adds a third dimension to the gameplay, allowing the snake to move in three-dimensional space.

3. Snake with Power-Ups: Power-ups can provide the snake with special abilities such as speed boosts, invincibility, or the ability to pass through walls.

4. Invisible Snake: The snake is invisible, except for its head, making it more challenging for the player to control and navigate.

5. Maze Snake: The game is set in a maze-like environment with walls and obstacles that the snake must navigate around.